Negative Feedback Synchronizes Islets of Langerhans

Insulin is released from the pancreas in pulses with a period of ∼ 5 min. These oscillatory insulin levels are essential for proper liver utilization and perturbed pulsatility is observed in type 2 diabetes. What coordinates the many islets of Langerhans throughout the pancreas to produce unified os...

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Bibliografske podrobnosti
Main Authors: Dhumpa, Raghuram, Truong, Tuan M., Wang, Xue, Bertram, Richard, Roper, Michael G.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2014
Teme:
Systems Biophysics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052280/
https://ncbi.nlm.nih.gov/pubmed/24853756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.04.015
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