Ccdc6 knock-in mice develop thyroid hyperplasia associated to an enhanced CREB1 activity

CCDC6 was originally identified upon rearrangement with RET in human thyroid papillary carcinomas generating the RET/PTC1 oncogene. We have previously reported that CCDC6 interacts with CREB1 and represses its transcriptional activity. Since the function of at least one allele of CCDC6 is lost follo...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Leone, Vincenza, Langella, Concetta, Esposito, Francesco, Arra, Claudio, Palma, Giuseppe, Rea, Domenica, Paciello, Orlando, Merolla, Francesco, De Biase, Davide, Papparella, Serenella, Celetti, Angela, Fusco, Alfredo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558175/
https://ncbi.nlm.nih.gov/pubmed/25970781
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