MicroRNA-21 plays an oncogenic role by targeting FOXO1 and activating the PI3K/AKT pathway in diffuse large B-cell lymphoma

The prognostic implications of miR-21, miR-17-92 and miR-155 were evaluated in diffuse large B-cell lymphoma (DLBCL) patients, and novel mechanism by which miR-21 contributes to the oncogenesis of DLBCL by regulating FOXO1 and PI3K/AKT/mTOR pathway was investigated. The expressions of miR-21, miR-17...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Go, Heounjeong, Jang, Ji-Young, Kim, Pil-Jong, Kim, Young-Goo, Nam, Soo Jeong, Paik, Jin Ho, Kim, Tae Min, Heo, Dae Seog, Kim, Chul-Woo, Jeon, Yoon Kyung
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558134/
https://ncbi.nlm.nih.gov/pubmed/25909227
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