Vaccination Expands Antigen-Specific CD4(+) Memory T Cells and Mobilizes Bystander Central Memory T Cells

CD4(+) T helper memory (Th(mem)) cells influence both natural and vaccine-boosted immunity, but mechanisms for their maintenance remain unclear. Pro-survival signals from the common gamma-chain cytokines, in particular IL-7, appear important. Previously we showed in healthy volunteers that a booster...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Li Causi, Eleonora, Parikh, Suraj C., Chudley, Lindsey, Layfield, David M., Ottensmeier, Christian H., Stevenson, Freda K., Di Genova, Gianfranco
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557947/
https://ncbi.nlm.nih.gov/pubmed/26332995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136717
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