The exaggerated inflammatory response in Behçet's syndrome: identification of dysfunctional post-transcriptional regulation of the IFN-γ/CXCL10 IP-10 pathway

The mechanisms underlying the exaggerated inflammatory response in Behçet's syndrome (BS) remain poorly understood. We investigated the response of CD14(+) blood monocytes to interferon (IFN)-γ, focusing on the chemokine CXCL10. Chemokine synthesis and release were analysed at a protein and mRN...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Clin Exp Immunol
Κύριοι συγγραφείς: Ambrose, N, Khan, E, Ravindran, R, Lightstone, L, Abraham, S, Botto, M, Johns, M, Haskard, D O
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: John Wiley & Sons, Ltd 2015
Θέματα:
Translational
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557378/
https://ncbi.nlm.nih.gov/pubmed/25982097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12655
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