The exaggerated inflammatory response in Behçet's syndrome: identification of dysfunctional post-transcriptional regulation of the IFN-γ/CXCL10 IP-10 pathway

The mechanisms underlying the exaggerated inflammatory response in Behçet's syndrome (BS) remain poorly understood. We investigated the response of CD14(+) blood monocytes to interferon (IFN)-γ, focusing on the chemokine CXCL10. Chemokine synthesis and release were analysed at a protein and mRN...

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Detalhes bibliográficos
Publicado no:Clin Exp Immunol
Main Authors: Ambrose, N, Khan, E, Ravindran, R, Lightstone, L, Abraham, S, Botto, M, Johns, M, Haskard, D O
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Translational
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557378/
https://ncbi.nlm.nih.gov/pubmed/25982097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12655
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