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Tet-mediated imprinting erasure in H19 locus following reprogramming of spermatogonial stem cells to induced pluripotent stem cells

Selective methylation of CpG islands at imprinting control regions (ICR) determines the monoparental expression of a subset of genes. Currently, it is unclear whether artificial reprogramming induced by the expression of Yamanaka factors disrupts these marks and whether cell type of origin affects t...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Bermejo-Álvarez, P., Ramos-Ibeas, P., Park, K.E., Powell, A. P., Vansandt, L., Derek, Bickhart, Ramirez, M. A., Gutiérrez-Adán, A., Telugu, B. P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556992/
https://ncbi.nlm.nih.gov/pubmed/26328763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13691
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