Impact of SCP-2/SCP-x gene ablation and dietary cholesterol on hepatic lipid accumulation

While a high-cholesterol diet induces hepatic steatosis, the role of intracellular sterol carrier protein-2/sterol carrier protein-x (SCP-2/SCP-x) proteins is unknown. We hypothesized that ablating SCP-2/SCP-x [double knockout (DKO)] would impact hepatic lipids (cholesterol and cholesteryl ester), e...

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Dades bibliogràfiques
Publicat a:Am J Physiol Gastrointest Liver Physiol
Autors principals: Klipsic, Devon, Landrock, Danilo, Martin, Gregory G., McIntosh, Avery L., Landrock, Kerstin K., Mackie, John T., Schroeder, Friedhelm, Kier, Ann B.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
Matèries:
Liver and Biliary Tract Physiology/Pathophysiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556946/
https://ncbi.nlm.nih.gov/pubmed/26113298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00460.2014
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