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Animal Models of Gastrointestinal and Liver Diseases. The difficulty of animal modeling of pancreatic cancer for preclinical evaluation of therapeutics

Pancreatic ductal adenocarcinoma (PDAC) is relatively rare but extremely lethal. Standard cytotoxic therapeutics provide little benefit. To date, newer targeted therapeutics have also not been highly successful. Often novel therapeutics that have appeared to perform well in preclinical models have f...

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Opis bibliograficzny
Wydane w:Am J Physiol Gastrointest Liver Physiol
Główni autorzy: Logsdon, Craig D., Arumugam, Thiruvengadam, Ramachandran, Vijaya
Format: Artigo
Język:Inglês
Wydane: American Physiological Society 2015
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556944/
https://ncbi.nlm.nih.gov/pubmed/26159697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00169.2015
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