Ablation of islet endocrine cells by targeted expression of hormone-promoter-driven toxigenes.

Ontogenic relationships between the different types of endocrine cells in the islets of Langerhans were explored by generating transgenic mouse embryos in which cells transcribing the glucagon, insulin, or pancreatic polypeptide genes were destroyed through the promoter-targeted expression of the di...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Herrera, P L, Huarte, J, Zufferey, R, Nichols, A, Mermillod, B, Philippe, J, Muniesa, P, Sanvito, F, Orci, L, Vassalli, J D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45568/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7809163/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.26.12999
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