In vivo parameters influencing 2-Cys Prx oligomerization: The role of enzyme sulfinylation

2-Cys Prxs are H(2)O(2)-specific antioxidants that become inactivated by enzyme hyperoxidation at elevated H(2)O(2) levels. Although hyperoxidation restricts the antioxidant physiological role of these enzymes, it also allows the enzyme to become an efficient chaperone holdase. The critical molecula...

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Detalles Bibliográficos
Publicado en:Redox Biol
Main Authors: Noichri, Y., Palais, G., Ruby, V., D’Autreaux, B., Delaunay-Moisan, A., Nyström, T., Molin, M., Toledano, M.B.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556779/
https://ncbi.nlm.nih.gov/pubmed/26335398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.08.011
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