In vivo parameters influencing 2-Cys Prx oligomerization: The role of enzyme sulfinylation

2-Cys Prxs are H(2)O(2)-specific antioxidants that become inactivated by enzyme hyperoxidation at elevated H(2)O(2) levels. Although hyperoxidation restricts the antioxidant physiological role of these enzymes, it also allows the enzyme to become an efficient chaperone holdase. The critical molecula...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Noichri, Y., Palais, G., Ruby, V., D’Autreaux, B., Delaunay-Moisan, A., Nyström, T., Molin, M., Toledano, M.B.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556779/
https://ncbi.nlm.nih.gov/pubmed/26335398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.08.011
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