Quercetin induces cell cycle arrest and apoptosis in CD133(+) cancer stem cells of human colorectal HT29 cancer cell line and enhances anticancer effects of doxorubicin

OBJECTIVE(S): The colorectal cancer stem cells (CSCs) with the CD133(+) phenotype are a rare fraction of cancer cells with the ability of self-renewal, unlimited proliferation and resistance to treatment. Quercetin has anticancer effects with the advantage of exhibiting low side effects. Therefore,...

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Publicat a:Iran J Basic Med Sci
Autors principals: Atashpour, Shekoufeh, Fouladdel, Shamileh, Movahhed, Tahereh Komeili, Barzegar, Elmira, Ghahremani, Mohammad Hossein, Ostad, Seyed Nasser, Azizi, Ebrahim
Format: Artigo
Idioma:Inglês
Publicat: Mashhad University of Medical Sciences 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556754/
https://ncbi.nlm.nih.gov/pubmed/26351552
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