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Are Quasi-Steady-State Approximated Models Suitable for Quantifying Intrinsic Noise Accurately?

Large gene regulatory networks (GRN) are often modeled with quasi-steady-state approximation (QSSA) to reduce the huge computational time required for intrinsic noise quantification using Gillespie stochastic simulation algorithm (SSA). However, the question still remains whether the stochastic QSSA...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Sengupta, Dola, Kar, Sandip
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556639/
https://ncbi.nlm.nih.gov/pubmed/26327626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136668
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