The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine

The disease caused by Plasmodium falciparum (Pf) involves different clinical manifestations that, cumulatively, kill hundreds of thousands every year. Placental malaria (PM) is one such manifestation in which Pf infected erythrocytes (IE) bind to chondroitin sulphate A (CSA) through expression of VA...

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發表在:PLoS One
Main Authors: Nielsen, Morten A., Resende, Mafalda, de Jongh, Willem A., Ditlev, Sisse B., Mordmüller, Benjamin, Houard, Sophie, Ndam, Nicaise Tuikue, Agerbæk, Mette Ø., Hamborg, Mette, Massougbodji, Achille, Issifou, Saddou, Strøbæk, Anette, Poulsen, Lars, Leroy, Odile, Kremsner, Peter G., Chippaux, Jean-Philippe, Luty, Adrian J. F., Deloron, Philippe, Theander, Thor G., Dyring, Charlotte, Salanti, Ali
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556615/
https://ncbi.nlm.nih.gov/pubmed/26327283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135406
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