Genipin Suppresses NLRP3 Inflammasome Activation Through Uncoupling Protein-2

Incomplete clearance of apoptotic cells and reactive oxygen species (ROS) release are known to trigger inflammasome activation causing severe inflammation in acute lung injury and various metabolic and autoimmune diseases. Moreover, it has been reported that apoptotic cell clearance and ROS-mediated...

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Publié dans:Cell Immunol
Auteurs principaux: Rajanbabu, Venugopal, Galam, Lakshmi, Fukumoto, Jutaro, Enciso, Juan, Tadikonda, Pratima, Lane, Troy N., Bandyopadhyay, Sayantani, Parthasarathy, Prasanna Tamarapu, Cho, Young, Cho, Seong Ho, Lee, Yong Chul, Lockey, Richard F., Kolliputi, Narasaiah
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556539/
https://ncbi.nlm.nih.gov/pubmed/26123077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2015.06.002
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