Changing EDSS Progression in Placebo Cohorts in Relapsing MS: A Systematic Review and Meta-Regression

BACKGROUND: Recent systematic reviews of randomised controlled trials (RCTs) in relapsing multiple sclerosis (RMS) revealed a decrease in placebo annualized relapse rates (ARR) over the past two decades. Furthermore, regression to the mean effects were observed in ARR and MRI lesion counts. It is un...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Röver, Christian, Nicholas, Richard, Straube, Sebastian, Friede, Tim
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556534/
https://ncbi.nlm.nih.gov/pubmed/26327532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137052
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