Genetics of Plasminogen Activator Inhibitor-1 (PAI-1) in a Ghanaian Population

Plasminogen activator inhibitor 1 (PAI-1), a major modulator of the fibrinolytic system, is an important factor in cardiovascular disease (CVD) susceptibility and severity. PAI-1 is highly heritable, but the few genes associated with it explain only a small portion of its variation. Studies of PAI-1...

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Опубликовано в: :PLoS One
Главные авторы: White, Marquitta J., Kodaman, Nuri M., Harder, Reed H., Asselbergs, Folkert W., Vaughan, Douglas E., Brown, Nancy J., Moore, Jason H., Williams, Scott M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556460/
https://ncbi.nlm.nih.gov/pubmed/26322636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136379
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