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Epistatic Interactions in Genetic Regulation of t-PA and PAI-1 Levels in a Ghanaian Population
The proteins, tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1), act in concert to balance thrombus formation and degradation, thereby modulating the development of arterial thrombosis and excessive bleeding. PAI-1 is upregulated by the renin-angiotensin system (RAS),...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031598/ https://ncbi.nlm.nih.gov/pubmed/21304999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016639 |
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