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Rli1/ABCE1 recycles terminating ribosomes and controls translation reinitiation in 3′UTRs in vivo
To study the function of ABCE1/Rli1 in vivo, we used ribosome profiling and biochemistry to characterize its contribution to ribosome recycling. When Rli1 levels were diminished, 80S ribosomes accumulated both at stop codons and in the adjoining 3′UTRs of most messenger RNAs. Frequently these riboso...
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| 出版年: | Cell |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4556345/ https://ncbi.nlm.nih.gov/pubmed/26276635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.07.041 |
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