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Novel piperine-loaded Tween-integrated monoolein cubosomes as brain-targeted oral nanomedicine in Alzheimer’s disease: pharmaceutical, biological, and toxicological studies

Alzheimer’s disease (AD) is one of the most patient devastating central nervous system diseases with no curative therapy. An effective oral therapy with brain-targeting potential is required that is hampered by blood–brain barrier. Piperine (PIP) is a natural alkaloid with memory enhancing potential...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Elnaggar, Yosra SR, Etman, Samar M, Abdelmonsif, Doaa A, Abdallah, Ossama Y
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556290/
https://ncbi.nlm.nih.gov/pubmed/26346130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S87336
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