Measurement of Human Cytochrome P450 Enzyme Induction Based on Mesalazine and Mosapride Citrate Treatments Using a Luminescent Assay

Drug metabolism mostly occurs in the liver. Cytochrome P450 (CYP) is a drug-metabolizing enzyme that is responsible for many important drug metabolism reactions. Recently, the US FDA and EU EMA have suggested that CYP enzyme induction can be measured by both enzymatic activity and mRNA expression. H...

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Detalhes bibliográficos
Publicado no:Biomol Ther (Seoul)
Main Authors: Kim, Young-Hoon, Bae, Young-Ji, Kim, Hyung Soo, Cha, Hey-Jin, Yun, Jae-Suk, Shin, Ji-Soon, Seong, Won-Keun, Lee, Yong-Moon, Han, Kyoung-Moon
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Applied Pharmacology 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556210/
https://ncbi.nlm.nih.gov/pubmed/26336590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2015.041
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