Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions

Deciphering the impact of genetic variants on gene regulation is fundamental to understanding human disease. Although gene regulation often involves long-range interactions, it is unknown to what extent non-coding genetic variants influence distal molecular phenotypes. Here, we integrate chromatin p...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell
Asıl Yazarlar: Grubert, Fabian, Zaugg, Judith B., Kasowski, Maya, Ursu, Oana, Spacek, Damek V., Martin, Alicia R., Greenside, Peyton, Srivas, Rohith, Phanstiel, Doug H., Pekowska, Aleksandra, Heidari, Nastaran, Euskirchen, Ghia, Huber, Wolfgang, Pritchard, Jonathan K., Bustamante, Carlos D., Steinmetz, Lars M., Kundaje, Anshul, Snyder, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556133/
https://ncbi.nlm.nih.gov/pubmed/26300125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.07.048
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