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Met tyrosine kinase inhibitor, PF-2341066, suppresses growth and invasion of nasopharyngeal carcinoma

PURPOSE: We explored the effect of hepatocyte growth factor (HGF)/Met signaling pathway on nasopharyngeal carcinoma (NPC) cells in vitro and in vivo, and investigated the ability of Met tyrosine kinase inhibitor (TKI) to block HGF-induced biological signaling. EXPERIMENTAL DESIGN: Met TKI inhibitor...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zhao, Yuanyuan, Zhang, Jing, Tian, Ying, Xue, Cong, Hu, Zhihuang, Zhang, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555972/
https://ncbi.nlm.nih.gov/pubmed/26345996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S85837
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