Met tyrosine kinase inhibitor, PF-2341066, suppresses growth and invasion of nasopharyngeal carcinoma

PURPOSE: We explored the effect of hepatocyte growth factor (HGF)/Met signaling pathway on nasopharyngeal carcinoma (NPC) cells in vitro and in vivo, and investigated the ability of Met tyrosine kinase inhibitor (TKI) to block HGF-induced biological signaling. EXPERIMENTAL DESIGN: Met TKI inhibitor...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Zhao, Yuanyuan, Zhang, Jing, Tian, Ying, Xue, Cong, Hu, Zhihuang, Zhang, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555972/
https://ncbi.nlm.nih.gov/pubmed/26345996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S85837
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