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A New Paradigm for XOR-Catalyzed Reactive Species Generation in the Endothelium

A plethora of vascular pathologies is associated with inflammation, hypoxia and elevated rates of reactive species generation. A critical source of these reactive species is the purine catabolizing enzyme xanthine oxidoreductase (XOR) as numerous reports over the past 30 years have demonstrated XOR...

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Dettagli Bibliografici
Pubblicato in:Pharmacol Rep
Autore principale: Kelley, Eric E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555844/
https://ncbi.nlm.nih.gov/pubmed/26321266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharep.2015.05.004
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