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Overexpression of the BMP4/SMAD signaling pathway in skull base chordomas is associated with poor prognosis
Chordomas are rare, locally invasive tumors with characteristic expression of the T-box transcription factor Brachyury. Little is yet known of the molecular events involved in the development of these tumors. Bone morphogenesis protein 4 (BMP4) signaling, which acts upstream of Brachyury in embryoni...
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| Publicado no: | Int J Clin Exp Pathol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
e-Century Publishing Corporation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4555724/ https://ncbi.nlm.nih.gov/pubmed/26339396 |
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