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Overexpression of the BMP4/SMAD signaling pathway in skull base chordomas is associated with poor prognosis

Chordomas are rare, locally invasive tumors with characteristic expression of the T-box transcription factor Brachyury. Little is yet known of the molecular events involved in the development of these tumors. Bone morphogenesis protein 4 (BMP4) signaling, which acts upstream of Brachyury in embryoni...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Clin Exp Pathol
Egile Nagusiak: Feng, Yanjun, Zhang, Qiuhang, Wang, Zhenlin, Yan, Bo, Wei, Wei, Li, Pu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: e-Century Publishing Corporation 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555724/
https://ncbi.nlm.nih.gov/pubmed/26339396
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