The effects of Tmc1 Beethoven mutation on mechanotransducer channel function in cochlear hair cells

Sound stimuli are converted into electrical signals via gating of mechano-electrical transducer (MT) channels in the hair cell stereociliary bundle. The molecular composition of the MT channel is still not fully established, although transmembrane channel–like protein isoform 1 (TMC1) may be one com...

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Bibliographic Details
Published in:J Gen Physiol
Main Authors: Beurg, Maryline, Goldring, Adam C., Fettiplace, Robert
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2015
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555472/
https://ncbi.nlm.nih.gov/pubmed/26324676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511458
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