Simultaneous suppression of the MAP kinase and NF-κB pathways provides a robust therapeutic potential for thyroid cancer

The MAP kinase and NF-κB signaling pathways play an important role in thyroid cancer tumorigenesis. We aimed to examine the therapeutic potential of dually targeting the two pathways using AZD6244 and Bortezomib in combination. We evaluated their effects on cell proliferation, cell-cycle progression...

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Publicat a:Cancer Lett
Autors principals: Tsumagari, Koji, Abd Elmageed, Zakaria Y., Sholl, Andrew B., Friedlander, Paul, Abdraboh, Mohamed, Xing, Mingzhao, Boulares, A. Hamid, Kandil, Emad
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555189/
https://ncbi.nlm.nih.gov/pubmed/26208433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.07.011
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