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Silica bioreplication preserves three-dimensional spheroid structures of human pluripotent stem cells and HepG2 cells

Three-dimensional (3D) cell cultures produce more in vivo-like multicellular structures such as spheroids that cannot be obtained in two-dimensional (2D) cell cultures. Thus, they are increasingly employed as models for cancer and drug research, as well as tissue engineering. It has proven challengi...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Lou, Yan-Ru, Kanninen, Liisa, Kaehr, Bryan, Townson, Jason L., Niklander, Johanna, Harjumäki, Riina, Jeffrey Brinker, C., Yliperttula, Marjo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555166/
https://ncbi.nlm.nih.gov/pubmed/26323570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13635
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