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PrP charge structure encodes interdomain interactions

Almost all proteins contain charged residues, and their chain distribution is tailored to fulfill essential ionic interactions for folding, binding and catalysis. Among proteins, the hinged two-domain chain of the cellular prion protein (PrP(C)) exhibits a peculiar charge structure with unclear cons...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Martínez, Javier, Sánchez, Rosa, Castellanos, Milagros, Makarava, Natallia, Aguzzi, Adriano, Baskakov, Ilia V., Gasset, María
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555102/
https://ncbi.nlm.nih.gov/pubmed/26323476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13623
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