Cytokines and growth factors cross-link heparan sulfate

The glycosaminoglycan heparan sulfate (HS), present at the surface of most cells and ubiquitous in extracellular matrix, binds many soluble extracellular signalling molecules such as chemokines and growth factors, and regulates their transport and effector functions. It is, however, unknown whether...

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Dettagli Bibliografici
Pubblicato in:Open Biol
Autori principali: Migliorini, Elisa, Thakar, Dhruv, Kühnle, Jens, Sadir, Rabia, Dyer, Douglas P., Li, Yong, Sun, Changye, Volkman, Brian F., Handel, Tracy M., Coche-Guerente, Liliane, Fernig, David G., Lortat-Jacob, Hugues, Richter, Ralf P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554917/
https://ncbi.nlm.nih.gov/pubmed/26269427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150046
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