Cytokines and growth factors cross-link heparan sulfate

The glycosaminoglycan heparan sulfate (HS), present at the surface of most cells and ubiquitous in extracellular matrix, binds many soluble extracellular signalling molecules such as chemokines and growth factors, and regulates their transport and effector functions. It is, however, unknown whether...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Migliorini, Elisa, Thakar, Dhruv, Kühnle, Jens, Sadir, Rabia, Dyer, Douglas P., Li, Yong, Sun, Changye, Volkman, Brian F., Handel, Tracy M., Coche-Guerente, Liliane, Fernig, David G., Lortat-Jacob, Hugues, Richter, Ralf P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554917/
https://ncbi.nlm.nih.gov/pubmed/26269427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150046
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