Cytokines and growth factors cross-link heparan sulfate

The glycosaminoglycan heparan sulfate (HS), present at the surface of most cells and ubiquitous in extracellular matrix, binds many soluble extracellular signalling molecules such as chemokines and growth factors, and regulates their transport and effector functions. It is, however, unknown whether...

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Publicado en:Open Biol
Autores principales: Migliorini, Elisa, Thakar, Dhruv, Kühnle, Jens, Sadir, Rabia, Dyer, Douglas P., Li, Yong, Sun, Changye, Volkman, Brian F., Handel, Tracy M., Coche-Guerente, Liliane, Fernig, David G., Lortat-Jacob, Hugues, Richter, Ralf P.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554917/
https://ncbi.nlm.nih.gov/pubmed/26269427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150046
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