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Lipid Insertion Domain Unfolding Regulates Protein Orientational Transition Behavior in a Lipid Bilayer

We have used coarse-grained (CG) and united atom (UA) molecular dynamics simulations to explore the mechanisms of protein orientational transition of a model peptide (Aβ(42)) in a phosphatidylcholine/cholesterol (PC/CHO) lipid bilayer. We started with an inserted state of Aβ(42) containing a folded...

詳細記述

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書誌詳細
出版年:Biophys Chem
主要な著者: Cheng, Kwan Hon, Qiu, Liming, Cheng, Sara Y., Vaughn, Mark W.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554884/
https://ncbi.nlm.nih.gov/pubmed/26164502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2015.06.011
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