Llwytho...

Lipid Insertion Domain Unfolding Regulates Protein Orientational Transition Behavior in a Lipid Bilayer

We have used coarse-grained (CG) and united atom (UA) molecular dynamics simulations to explore the mechanisms of protein orientational transition of a model peptide (Aβ(42)) in a phosphatidylcholine/cholesterol (PC/CHO) lipid bilayer. We started with an inserted state of Aβ(42) containing a folded...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys Chem
Prif Awduron: Cheng, Kwan Hon, Qiu, Liming, Cheng, Sara Y., Vaughn, Mark W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554884/
https://ncbi.nlm.nih.gov/pubmed/26164502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2015.06.011
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!