Targeting the isoprenoid pathway to abrogate progression of pulmonary fibrosis

Fibrotic remodeling in lung injury is a major cause of morbidity. The mechanism that mediates the ongoing fibrosis is unclear, and there is no available treatment to abate the aberrant repair. Reactive oxygen species (ROS) have a critical role in inducing fibrosis by modulating extracellular matrix...

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Vydáno v:Free Radic Biol Med
Hlavní autoři: Osborn-Heaford, Heather L., Murthy, Shubha, Gu, Linlin, Larson-Casey, Jennifer L., Ryan, Alan J., Shi, Lei, Glogauer, Michael, Neighbors, Jeffrey D., Hohl, Raymond, Carter, A. Brent
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554879/
https://ncbi.nlm.nih.gov/pubmed/25958207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.04.031
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