Prognostic Significance of Diffuse Large B-Cell Lymphoma Cell of Origin Determined by Digital Gene Expression in Formalin-Fixed Paraffin-Embedded Tissue Biopsies

PURPOSE: To evaluate the prognostic impact of cell-of-origin (COO) subgroups, assigned using the recently described gene expression–based Lymph2Cx assay in comparison with International Prognostic Index (IPI) score and MYC/BCL2 coexpression status (dual expressers). PATIENTS AND METHODS: Reproducibi...

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Veröffentlicht in:J Clin Oncol
Hauptverfasser: Scott, David W., Mottok, Anja, Ennishi, Daisuke, Wright, George W., Farinha, Pedro, Ben-Neriah, Susana, Kridel, Robert, Barry, Garrett S., Hother, Christoffer, Abrisqueta, Pau, Boyle, Merrill, Meissner, Barbara, Telenius, Adele, Savage, Kerry J., Sehn, Laurie H., Slack, Graham W., Steidl, Christian, Staudt, Louis M., Connors, Joseph M., Rimsza, Lisa M., Gascoyne, Randy D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554747/
https://ncbi.nlm.nih.gov/pubmed/26240231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.60.2383
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