Prognostic Significance of Diffuse Large B-Cell Lymphoma Cell of Origin Determined by Digital Gene Expression in Formalin-Fixed Paraffin-Embedded Tissue Biopsies

PURPOSE: To evaluate the prognostic impact of cell-of-origin (COO) subgroups, assigned using the recently described gene expression–based Lymph2Cx assay in comparison with International Prognostic Index (IPI) score and MYC/BCL2 coexpression status (dual expressers). PATIENTS AND METHODS: Reproducibi...

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Vydáno v:J Clin Oncol
Hlavní autoři: Scott, David W., Mottok, Anja, Ennishi, Daisuke, Wright, George W., Farinha, Pedro, Ben-Neriah, Susana, Kridel, Robert, Barry, Garrett S., Hother, Christoffer, Abrisqueta, Pau, Boyle, Merrill, Meissner, Barbara, Telenius, Adele, Savage, Kerry J., Sehn, Laurie H., Slack, Graham W., Steidl, Christian, Staudt, Louis M., Connors, Joseph M., Rimsza, Lisa M., Gascoyne, Randy D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554747/
https://ncbi.nlm.nih.gov/pubmed/26240231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.60.2383
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