A carregar...
Direct Chemical Activation of a Rationally Engineered Signaling Enzyme
Few chemical strategies for activating enzymes have been developed. Here we show that a biarsenical compound (FlAsH) can directly activate a rationally engineered protein tyrosine phosphatase (Shp2 PTP) via disruption of autoinhibitory interactions between Shp2’s N-terminal SH2 domain and its PTP do...
Na minha lista:
| Publicado no: | Chembiochem |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4554683/ https://ncbi.nlm.nih.gov/pubmed/26063205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500245 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|