The ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastoma

Glioblastoma multiforme (GBM) is the most aggressive malignant brain tumour in humans and is highly resistant to current treatment modalities. We have explored the combined treatment of the endoplasmic reticulum (ER) stress-inducing agent 2,5-dimethyl-celecoxib (DMC) and TNF-related apoptosis-induci...

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Dades bibliogràfiques
Publicat a:Springerplus
Autors principals: van Roosmalen, Ingrid A M, Reis, Carlos R, Setroikromo, Rita, Yuvaraj, Saravanan, Joseph, Justin V, Tepper, Pieter G, Kruyt, Frank A E, Quax, Wim J
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554544/
https://ncbi.nlm.nih.gov/pubmed/26331107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-495
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