The ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastoma

Glioblastoma multiforme (GBM) is the most aggressive malignant brain tumour in humans and is highly resistant to current treatment modalities. We have explored the combined treatment of the endoplasmic reticulum (ER) stress-inducing agent 2,5-dimethyl-celecoxib (DMC) and TNF-related apoptosis-induci...

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Detalhes bibliográficos
Publicado no:Springerplus
Main Authors: van Roosmalen, Ingrid A M, Reis, Carlos R, Setroikromo, Rita, Yuvaraj, Saravanan, Joseph, Justin V, Tepper, Pieter G, Kruyt, Frank A E, Quax, Wim J
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554544/
https://ncbi.nlm.nih.gov/pubmed/26331107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-495
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