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Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier

To clarify the significance of immunoglobulin G autoantibody specific for the astrocyte water channel aquaporin-4 in cerebrospinal fluid, aquaporin-4-immunoglobulin G from a neuromyelitis optica patient was administered intrathecally to naïve mice, and the distribution and pathogenic impact was eval...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Asgari, Nasrin, Berg, Carsten Tue, Mørch, Marlene Thorsen, Khorooshi, Reza, Owens, Trevor
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554446/
https://ncbi.nlm.nih.gov/pubmed/26339679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.221
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