Modification of paclitaxel-loaded solid lipid nanoparticles with 2-hydroxypropyl-β-cyclodextrin enhances absorption and reduces nephrotoxicity associated with intravenous injection

BACKGROUND: Paclitaxel (PTX) solid lipid nanoparticles (SLNs) modified with 2-hydroxypropyl-β-cyclodextrin (HPCD) were evaluated for their ability to enhance PTX absorption and reduce the nephrotoxicity accompanying intravenous administration. METHODS: PTX-loaded SLNs (PS) and PTX-loaded SLNs modifi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Int J Nanomedicine
Hlavní autoři: Baek, Jong-Suep, Kim, Ju-Heon, Park, Jeong-Sook, Cho, Cheong-Weon
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554395/
https://ncbi.nlm.nih.gov/pubmed/26347363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S86474
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky