Modification of paclitaxel-loaded solid lipid nanoparticles with 2-hydroxypropyl-β-cyclodextrin enhances absorption and reduces nephrotoxicity associated with intravenous injection

BACKGROUND: Paclitaxel (PTX) solid lipid nanoparticles (SLNs) modified with 2-hydroxypropyl-β-cyclodextrin (HPCD) were evaluated for their ability to enhance PTX absorption and reduce the nephrotoxicity accompanying intravenous administration. METHODS: PTX-loaded SLNs (PS) and PTX-loaded SLNs modifi...

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Bibliografische gegevens
Gepubliceerd in:Int J Nanomedicine
Hoofdauteurs: Baek, Jong-Suep, Kim, Ju-Heon, Park, Jeong-Sook, Cho, Cheong-Weon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2015
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554395/
https://ncbi.nlm.nih.gov/pubmed/26347363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S86474
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