Single-Dose Pharmacokinetics of Intravenous Itraconazole and Hydroxypropyl-β-Cyclodextrin in Infants, Children, and Adolescents

This investigation was designed to evaluate the single-dose pharmacokinetics of itraconazole, hydroxyitraconazole, and hydroxypropyl-β-cyclodextrin (HP-β-CD) after intravenous administration to children at risk for fungal infection. Thirty-three children aged 7 months to 17 years received a single d...

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Detalhes bibliográficos
Main Authors: Abdel-Rahman, Susan M., Jacobs, Richard F., Massarella, Joseph, Kauffman, Ralph E., Bradley, John S., Kimko, Hui C., Kearns, Gregory L., Shalayda, Kevin, Curtin, Christopher, Maldonado, Samuel D., Blumer, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932535/
https://ncbi.nlm.nih.gov/pubmed/17517842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00297-07
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