Sublethal dose of irradiation enhances invasion of malignant glioma cells through p53-MMP 2 pathway in U87MG mouse brain tumor model

BACKGROUND: Glioblastoma is a highly lethal neoplasm that frequently recurs locally after radiotherapy, and most of these recurrences originate from near the irradiated target field. In the present study, we identified the effects of radiation on glioma invasion and p53, TIMP-2, and MMP-2 expression...

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Опубликовано в: :Radiat Oncol
Главные авторы: Pei, Jian, Park, In-Ho, Ryu, Hyang-Hwa, Li, Song-Yuan, Li, Chun-Hao, Lim, Sa-Hoe, Wen, Min, Jang, Woo-Youl, Jung, Shin
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554349/
https://ncbi.nlm.nih.gov/pubmed/26245666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-015-0475-8
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