Sublethal dose of irradiation enhances invasion of malignant glioma cells through p53-MMP 2 pathway in U87MG mouse brain tumor model

BACKGROUND: Glioblastoma is a highly lethal neoplasm that frequently recurs locally after radiotherapy, and most of these recurrences originate from near the irradiated target field. In the present study, we identified the effects of radiation on glioma invasion and p53, TIMP-2, and MMP-2 expression...

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Detalhes bibliográficos
Publicado no:Radiat Oncol
Main Authors: Pei, Jian, Park, In-Ho, Ryu, Hyang-Hwa, Li, Song-Yuan, Li, Chun-Hao, Lim, Sa-Hoe, Wen, Min, Jang, Woo-Youl, Jung, Shin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554349/
https://ncbi.nlm.nih.gov/pubmed/26245666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-015-0475-8
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