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Sublethal dose of irradiation enhances invasion of malignant glioma cells through p53-MMP 2 pathway in U87MG mouse brain tumor model

BACKGROUND: Glioblastoma is a highly lethal neoplasm that frequently recurs locally after radiotherapy, and most of these recurrences originate from near the irradiated target field. In the present study, we identified the effects of radiation on glioma invasion and p53, TIMP-2, and MMP-2 expression...

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Bibliografiske detaljer
Udgivet i:Radiat Oncol
Main Authors: Pei, Jian, Park, In-Ho, Ryu, Hyang-Hwa, Li, Song-Yuan, Li, Chun-Hao, Lim, Sa-Hoe, Wen, Min, Jang, Woo-Youl, Jung, Shin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554349/
https://ncbi.nlm.nih.gov/pubmed/26245666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-015-0475-8
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