The new nitric oxide donor cyclohexane nitrate induces vasorelaxation, hypotension, and antihypertensive effects via NO/cGMP/PKG pathway

We investigated the cardiovascular effects induced by the nitric oxide donor Cyclohexane Nitrate (HEX). Vasodilatation, NO release and the effects of acute or sub-chronic treatment with HEX on cardiovascular parameters were evaluated. HEX induced endothelium-independent vasodilatation (Maximum effec...

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Publicat a:Front Physiol
Autors principals: Mendes-Júnior, Leônidas das G., Guimarães, Driele D., Gadelha, Danilo D. A., Diniz, Thiago F., Brandão, Maria C. R., Athayde-Filho, Petrônio F., Lemos, Virginia S., França-Silva, Maria do S., Braga, Valdir A.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553900/
https://ncbi.nlm.nih.gov/pubmed/26379557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00243
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