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Analysis of nanopore data using hidden Markov models

Motivation: Nanopore-based sequencing techniques can reconstruct properties of biosequences by analyzing the sequence-dependent ionic current steps produced as biomolecules pass through a pore. Typically this involves alignment of new data to a reference, where both reference construction and alignm...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Schreiber, Jacob, Karplus, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553831/
https://ncbi.nlm.nih.gov/pubmed/25649617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv046
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