Breakthrough of SIV strain smE660 challenge in SIV strain mac239-vaccinated rhesus macaques despite potent autologous neutralizing antibody responses

Although the correlates of immunological protection from human immunodeficiency virus or simian immunodeficiency virus infection remain incompletely understood, it is generally believed that medium to high titers of serum neutralizing antibodies (nAbs) against the challenge virus will prevent infect...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Burton, Samantha L., Kilgore, Katie M., Smith, S. Abigail, Reddy, Sharmila, Hunter, Eric, Robinson, Harriet L., Silvestri, Guido, Amara, Rama R., Derdeyn, Cynthia A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553804/
https://ncbi.nlm.nih.gov/pubmed/26261312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509731112
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