Breakthrough of SIV strain smE660 challenge in SIV strain mac239-vaccinated rhesus macaques despite potent autologous neutralizing antibody responses

Although the correlates of immunological protection from human immunodeficiency virus or simian immunodeficiency virus infection remain incompletely understood, it is generally believed that medium to high titers of serum neutralizing antibodies (nAbs) against the challenge virus will prevent infect...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Burton, Samantha L., Kilgore, Katie M., Smith, S. Abigail, Reddy, Sharmila, Hunter, Eric, Robinson, Harriet L., Silvestri, Guido, Amara, Rama R., Derdeyn, Cynthia A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553804/
https://ncbi.nlm.nih.gov/pubmed/26261312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509731112
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