Breakthrough of SIV strain smE660 challenge in SIV strain mac239-vaccinated rhesus macaques despite potent autologous neutralizing antibody responses

Although the correlates of immunological protection from human immunodeficiency virus or simian immunodeficiency virus infection remain incompletely understood, it is generally believed that medium to high titers of serum neutralizing antibodies (nAbs) against the challenge virus will prevent infect...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Burton, Samantha L., Kilgore, Katie M., Smith, S. Abigail, Reddy, Sharmila, Hunter, Eric, Robinson, Harriet L., Silvestri, Guido, Amara, Rama R., Derdeyn, Cynthia A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553804/
https://ncbi.nlm.nih.gov/pubmed/26261312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509731112
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