Systems biology definition of the core proteome of metabolism and expression is consistent with high-throughput data

Finding the minimal set of gene functions needed to sustain life is of both fundamental and practical importance. Minimal gene lists have been proposed by using comparative genomics-based core proteome definitions. A definition of a core proteome that is supported by empirical data, is understood at...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yang, Laurence, Tan, Justin, O’Brien, Edward J., Monk, Jonathan M., Kim, Donghyuk, Li, Howard J., Charusanti, Pep, Ebrahim, Ali, Lloyd, Colton J., Yurkovich, James T., Du, Bin, Dräger, Andreas, Thomas, Alex, Sun, Yuekai, Saunders, Michael A., Palsson, Bernhard O.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553782/
https://ncbi.nlm.nih.gov/pubmed/26261351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501384112
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