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Amelioration of Bleomycin-induced Pulmonary Fibrosis of Rats by an Aldose Reductase Inhibitor, Epalrestat

Aldose reductase (AR) is known to play a crucial role in the mediation of diabetic and cardiovascular complications. Recently, several studies have demonstrated that allergen-induced airway remodeling and ovalbumin-induced asthma is mediated by AR. Epalrestat is an aldose reductase inhibitor that is...

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Pubblicato in:Korean J Physiol Pharmacol
Autori principali: Li, Xianwei, Shen, Yuanyuan, Lu, Yining, Yang, Jieren
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Physiological Society and The Korean Society of Pharmacology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553399/
https://ncbi.nlm.nih.gov/pubmed/26330752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2015.19.5.401
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