Endostatin, an angiogenesis inhibitor, ameliorates bleomycin-induced pulmonary fibrosis in rats

BACKGROUND: Recent evidence has demonstrated the role of angiogenesis in the pathogenesis of pulmonary fibrosis. Endostatin, a proteolytic fragment of collagen XVIII, is a potent inhibitor of angiogenesis. The aim of our study was to assess whether endostatin has beneficial effects on bleomycin (BLM...

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Detalhes bibliográficos
Main Authors: Wan, Yun-Yan, Tian, Guang-Yan, Guo, Hai-Sheng, Kang, Yan-Meng, Yao, Zhou-Hong, Li, Xi-Li, Liu, Qing-Hua, Lin, Dian-Jie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668162/
https://ncbi.nlm.nih.gov/pubmed/23688086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-56
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